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The In Vitro Redundant Enzymes PurN and PurT Are Both Essential for Systemic Infection of Mice in Salmonella enterica Serovar Typhimurium

Metabolic enzymes show a high degree of redundancy, and for that reason they are generally ignored in searches for novel targets for anti-infective substances. The enzymes PurN and PurT are redundant in vitro in Salmonella enterica serovar Typhimurium, in which they perform the third step of purine...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Jelsbak, Lotte, Mortensen, Mie I. B., Kilstrup, Mogens, Olsen, John E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936368/
https://ncbi.nlm.nih.gov/pubmed/27113361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00182-16
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