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Metformin treatment modulates the tumour-induced wasting effects in muscle protein metabolism minimising the cachexia in tumour-bearing rats

BACKGROUND: Cancer-cachexia state frequently induces both fat and protein wasting, leading to death. In this way, the knowledge of the mechanism of drugs and their side effects can be a new feature to treat and to have success, contributing to a better life quality for these patients. Metformin is a...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Oliveira, André G., Gomes-Marcondes, Maria Cristina C.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936094/
https://ncbi.nlm.nih.gov/pubmed/27388367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2424-9
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