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QT interval prolongation and torsade de pointes: Synergistic effect of flecainide and H(1) receptor antagonists

A high percentage of patients having atrial fibrillation (AF) presents with paroxysmal AF. Flecainide, the prototypic class Ic anti-arrhythmic drug is the most effective drug to maintain sinus rhythm in this subgroup of patients, though the drug has potential pro-arrhythmic effects. Furthermore, the...

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Detalhes bibliográficos
Publicado no:J Pharmacol Pharmacother
Main Authors: Acosta-Materán, Carlos, Díaz-Oliva, Eloy, Fernández-Rodríguez, Diego, Hernández-Afonso, Julio
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936076/
https://ncbi.nlm.nih.gov/pubmed/27440957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0976-500X.184776
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