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Stiffness of the microenvironment upregulates ERBB2 expression in 3D cultures of MCF10A within the range of mammographic density

The effects of the stiffness of the microenvironment on the molecular response of 3D colony organization, at the maximum level of mammographic density (MD), are investigated. Phenotypic profiling reveals that 3D colony formation is heterogeneous and increased stiffness of the microenvironment, withi...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Cheng, Qingsu, Bilgin, Cemal Cagatay, Fonteney, Gerald, Chang, Hang, Henderson, Matthew, Han, Ju, Parvin, Bahram
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935956/
https://ncbi.nlm.nih.gov/pubmed/27383056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28987
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