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32 doses of bortezomib for desensitization is not well-tolerated and is associated with only modest reductions in anti-HLA antibody

BACKGROUND: We previously showed that bortezomib (BTZ) partially depletes plasma cells, yet has limited efficacy for desensitization in kidney transplant (KTx) candidates when up to 16 doses is given. METHODS: This study aimed to determine the safety and efficacy of 32 doses of BTZ (1.3mg/m(2) of bo...

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Detalhes bibliográficos
Publicado no:Transplantation
Main Authors: Gonzales, Manuel A. Moreno, Gandhi, Manish J., Schinstock, Carrie A., Moore, Natalie A., Smith, Byron H., Braaten, Nong Y., Stegall, Mark D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935916/
https://ncbi.nlm.nih.gov/pubmed/27379560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0000000000001330
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