miR-7a/b attenuates post-myocardial infarction remodeling and protects H9c2 cardiomyoblast against hypoxia-induced apoptosis involving Sp1 and PARP-1

miRs (microRNAs, miRNAs) intricately regulate physiological and pathological processes. Although miR-7a/b protects against cardiomyocyte injury in ischemia/reperfusion injury, the function of miR-7a/b in myocardial infarction (MI)-induced cardiac remodeling remains unclear. Here, we sought to invest...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Li, Rui, Geng, Hai-hua, Xiao, Jie, Qin, Xiao-teng, Wang, Fu, Xing, Jun-hui, Xia, Yan-fei, Mao, Yang, Liang, Jing-wen, Ji, Xiao-ping
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935883/
https://ncbi.nlm.nih.gov/pubmed/27384152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29082
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