Overexpression of Mycothiol Disulfide Reductase Enhances Corynebacterium glutamicum Robustness by Modulating Cellular Redox Homeostasis and Antioxidant Proteins under Oxidative Stress

Mycothiol (MSH) is the dominant low-molecular-weight thiol (LMWT) unique to high-(G+C)-content Gram-positive Actinobacteria, such as Corynebacterium glutamicum, and is oxidised into its disulfide form mycothiol disulfide (MSSM) under oxidative conditions. Mycothiol disulfide reductase (Mtr), an NADP...

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Gepubliceerd in:Sci Rep
Hoofdauteurs: Si, Meiru, Zhao, Chao, Zhang, Bing, Wei, Dawei, Chen, Keqi, Yang, Xu, Xiao, He, Shen, Xihui
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935862/
https://ncbi.nlm.nih.gov/pubmed/27383057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29491
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