A Simplified In vitro Experimental Model Encompasses the Essential Features of Sleep

In this paper, we show that neuronal assemblies plated on Micro Electrode Arrays present synchronized, low frequency firing patterns similar to in vivo slow wave oscillations, which are a key parameter of sleep-like state. Although neuronal cultures lack the characteristic high-frequency waves of wa...

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Bibliographic Details
Published in:Front Neurosci
Main Authors: Colombi, Ilaria, Tinarelli, Federico, Pasquale, Valentina, Tucci, Valter, Chiappalone, Michela
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2016
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935686/
https://ncbi.nlm.nih.gov/pubmed/27458335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2016.00315
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