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Interactions between Anandamide & Corticotropin-Releasing Hormone Signaling Modulate Human Amygdala Function & Risk for Anxiety Disorders: An Imaging Genetics Strategy for Modeling Molecular Interactions
BACKGROUND: Preclinical models reveal that stress-induced amygdala activity and impairment in fear extinction reflects reductions in anandamide driven by corticotropin-releasing hormone receptor type 1 (CRHR1) potentiation of the anandamide catabolic enzyme fatty acid amide hydrolase (FAAH). METHODS...
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| Publicado no: | Biol Psychiatry |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4935637/ https://ncbi.nlm.nih.gov/pubmed/26923505 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2015.12.021 |
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