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Akt Isoform-Dependent Regulation of ATP-Binding Cassette A1 Expression by Apolipoprotein E
We previously reported that apolipoprotein E (apoE) upregulates ATP-binding cassette transporter A1 (ABCA1) transcription through phosphatidylinositol 3-kinase (PI3K). Here we demonstrate that treatment of murine macrophages with human apoE3 enhanced Akt phosphorylation, and upregulated ABCA1 protei...
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| Publicado no: | Biochem Biophys Res Commun |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4935621/ https://ncbi.nlm.nih.gov/pubmed/27297104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2016.06.031 |
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