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Single nucleotide polymorphisms linked to mitochondrial uncoupling protein genes UCP2 and UCP3 affect mitochondrial metabolism and healthy aging in female nonagenarians

Energy expenditure decreases with age, but in the oldest-old, energy demand for maintenance of body functions increases with declining health. Uncoupling proteins have profound impact on mitochondrial metabolic processes; therefore, we focused attention on mitochondrial uncoupling protein genes. Alo...

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Bibliografiske detaljer
Udgivet i:Biogerontology
Main Authors: Kim, Sangkyu, Myers, Leann, Ravussin, Eric, Cherry, Katie E., Jazwinski, S. Michal
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935613/
https://ncbi.nlm.nih.gov/pubmed/26965008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10522-016-9643-y
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