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A splice variant of the myosin phosphatase regulatory subunit tunes arterial reactivity and suppresses response to salt loading
The cGMP activated kinase cGK1α is targeted to its substrates via leucine zipper (LZ)-mediated heterodimerization and thereby mediates vascular smooth muscle (VSM) relaxation. One target is myosin phosphatase (MP), which when activated by cGK1α results in VSM relaxation even in the presence of activ...
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| Publicado no: | Am J Physiol Heart Circ Physiol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4935519/ https://ncbi.nlm.nih.gov/pubmed/27084390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00869.2015 |
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