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Sex- and corticotropin-releasing factor receptor 2- dependent actions of urocortin 1 during inflammation

We investigated whether corticotropin-releasing factor receptor 2 (CRF(2)) and its high-affinity agonist urocortin 1 (Ucn1) mediate sex-specific signaling and immune responses. Intrarectal trinitrobenzene sulfonic acid was used to induce experimental colitis in wild-type, CRF(2) knockout (CRF(2)KO),...

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Detalhes bibliográficos
Publicado no:Am J Physiol Regul Integr Comp Physiol
Main Authors: Hasdemir, Burcu, Mhaske, Pallavi, Paruthiyil, Sreenivasan, Garnett, Elizabeth A., Heyman, Melvin B., Matloubian, Mehrdad, Bhargava, Aditi
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935495/
https://ncbi.nlm.nih.gov/pubmed/27053649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00445.2015
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