Insights into the pathogenesis of ulcerative colitis from a murine model of stasis-induced dysbiosis, colonic metaplasia, and genetic susceptibility

Gut dysbiosis, host genetics, and environmental triggers are implicated as causative factors in inflammatory bowel disease (IBD), yet mechanistic insights are lacking. Longitudinal analysis of ulcerative colitis (UC) patients following total colectomy with ileal anal anastomosis (IPAA) where >50%...

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Detalhes bibliográficos
Publicado no:Am J Physiol Gastrointest Liver Physiol
Main Authors: Ward, Marc A., Pierre, Joseph F., Leal, Raquel F., Huang, Yong, Shogan, Benjamin, Dalal, Sushila R., Weber, Christopher R., Leone, Vanessa A., Musch, Mark W., An, Gary C., Rao, Mrinalini C., Rubin, David T., Raffals, Laura E., Antonopoulos, Dionysios A., Sogin, Mitch L., Hyman, Neil H., Alverdy, John C., Chang, Eugene B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
Assuntos:
Microbiome and Host Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935476/
https://ncbi.nlm.nih.gov/pubmed/27079612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00017.2016
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