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ELKS controls the pool of readily releasable vesicles at excitatory synapses through its N-terminal coiled-coil domains

In a presynaptic nerve terminal, synaptic strength is determined by the pool of readily releasable vesicles (RRP) and the probability of release (P) of each RRP vesicle. These parameters are controlled at the active zone and vary across synapses, but how such synapse specific control is achieved is...

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Veröffentlicht in:eLife
Hauptverfasser: Held, Richard G, Liu, Changliang, Kaeser, Pascal S
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935463/
https://ncbi.nlm.nih.gov/pubmed/27253063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.14862
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