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Inhibiting myostatin signaling prevents femoral trabecular bone loss and microarchitecture deterioration in diet-induced obese rats

Besides resulting in a dramatic increase in skeletal muscle mass, myostatin (MSTN) deficiency has a positive effect on bone formation. However, the issue about whether blocking MSTN can inhibit obesity-induced bone loss has not been previously investigated. In the present study, we have evaluated th...

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Detalhes bibliográficos
Publicado no:Exp Biol Med (Maywood)
Main Authors: Tang, Liang, Yang, Xiaoying, Gao, Xiaohang, Du, Haiping, Han, Yanqi, Zhang, Didi, Wang, Zhiyuan, Sun, Lijun
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935442/
https://ncbi.nlm.nih.gov/pubmed/26438721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370215606814
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