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Protective phenotypes of club cells and alveolar macrophages are favored as part of endotoxin-mediated prevention of asthma

Atopic asthma is a chronic allergic disease that involves T-helper type 2 (Th2)-inflammation and airway remodeling. Bronchiolar club cells (CC) and alveolar macrophages (AM) are sentinel cells of airway barrier against inhaled injuries, where allergy induces mucous metaplasia of CC and the alternati...

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Detalhes bibliográficos
Publicado no:Exp Biol Med (Maywood)
Main Authors: García, Luciana N, Leimgruber, Carolina, Uribe Echevarría, Elisa M, Acosta, Patricio L, Brahamian, Jorge M, Polack, Fernando P, Miró, María S, Quintar, Amado A, Sotomayor, Claudia E, Maldonado, Cristina A
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935407/
https://ncbi.nlm.nih.gov/pubmed/25504013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370214562338
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