Ursodeoxycholyl lysophosphatidylethanolamide inhibits cholestasis- and hypoxia-induced apoptosis by upregulating antiapoptosis proteins

An increase of toxic bile acids such as glycochenodeoxycholic acid occurs during warm ischemia reperfusion causing cholestasis and damage in hepatocytes and intrahepatic biliary epithelial cells. We aim to test antiapoptosis effects of ursodeoxycholyl lysophosphatidylethanolamide under cholestatic i...

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Bibliographische Detailangaben
Veröffentlicht in:Exp Biol Med (Maywood)
Hauptverfasser: Sellinger, Myra, Xu, Weihong, Pathil, Anita, Stremmel, Wolfgang, Chamulitrat, Walee
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publications 2015
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935323/
https://ncbi.nlm.nih.gov/pubmed/25125499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370214547157
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