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From humble beginnings to success in the clinic: Chimeric antigen receptor-modified T-cells and implications for immunotherapy

In the past 50 years, disease burden has steadily shifted from infectious disease to cancer. Standard chemotherapy has long been the mainstay of cancer medical management, and despite vast efforts towards more targeted and personalized drug therapy, many cancers remain refractory to treatment, with...

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Detalhes bibliográficos
Publicado no:Exp Biol Med (Maywood)
Main Authors: Firor, Amelia E, Jares, Alexander, Ma, Yupo
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935283/
https://ncbi.nlm.nih.gov/pubmed/25956686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370215584936
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