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The distribution of plasma phenytoin levels in epileptic patients

Plasma phenytoin levels were estimated in 111 adult epileptic patients. A wide scatter of values was found, with over half outside the therapeutic limits of 10 to 20 μg/ml. Phenytoin tolerance tests carried out in five patients revealed a possible failure to metabolize the drug adequately in three o...

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Autori principali: Lascelles, P. T., Kocen, R. S., Reynolds, E. H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1970
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC493508/
https://ncbi.nlm.nih.gov/pubmed/5505677
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