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Interleukin-6 Induces Vascular Endothelial Growth Factor-C Expression via Src-FAK-STAT3 Signaling in Lymphatic Endothelial Cells
Elevated serum interleukin-6 (IL-6) levels correlates with tumor grade and poor prognosis in cancer patients. IL-6 has been shown to promote tumor lymphangiogenesis through vascular endothelial growth factor-C (VEGF-C) induction in tumor cells. We recently showed that IL-6 also induced VEGF-C expres...
Kaydedildi:
Yayımlandı: | PLoS One |
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Asıl Yazarlar: | , , , , , |
Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
Public Library of Science
2016
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4934912/ https://ncbi.nlm.nih.gov/pubmed/27383632 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0158839 |
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