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Genetic Dissection of Cardiac Remodeling in an Isoproterenol-Induced Heart Failure Mouse Model

We aimed to understand the genetic control of cardiac remodeling using an isoproterenol-induced heart failure model in mice, which allowed control of confounding factors in an experimental setting. We characterized the changes in cardiac structure and function in response to chronic isoproterenol in...

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Publicat a:PLoS Genet
Autors principals: Wang, Jessica Jen-Chu, Rau, Christoph, Avetisyan, Rozeta, Ren, Shuxun, Romay, Milagros C., Stolin, Gabriel, Gong, Ke Wei, Wang, Yibin, Lusis, Aldons J.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4934852/
https://ncbi.nlm.nih.gov/pubmed/27385019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006038
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