A DLL3-targeted antibody-drug conjugate eradicates high-grade pulmonary neuroendocrine tumor-initiating cells in vivo

The high-grade pulmonary neuroendocrine tumors, small cell lung cancer (SCLC) and large cell neuroendocrine carcinoma (LCNEC), remain among the most deadly malignancies. Therapies that effectively target and kill tumor-initiating cells (TICs) in these cancers should translate to improved patient sur...

詳細記述

保存先:
書誌詳細
出版年:Sci Transl Med
主要な著者: Saunders, Laura R., Bankovich, Alexander J., Anderson, Wade C., Aujay, Monette A., Bheddah, Sheila, Black, KristenAnn, Desai, Radhika, Escarpe, Paul A., Hampl, Johannes, Laysang, Amy, Liu, David, Lopez-Molina, Javier, Milton, Milly, Park, Albert, Pysz, Marybeth A., Shao, Hui, Slingerland, Brian, Torgov, Michael, Williams, Samuel A., Foord, Orit, Howard, Philip, Jassem, Jacek, Badzio, Andrzej, Czapiewski, Piotr, Harpole, David H., Dowlati, Afshin, Massion, Pierre P., Travis, William D., Pietanza, M. Catherine, Poirier, J. T., Rudin, Charles M., Stull, Robert A., Dylla, Scott J.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4934375/
https://ncbi.nlm.nih.gov/pubmed/26311731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aac9459
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料