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A novel mutant 10Ala/Arg together with mutant 144Ser/Arg of hepatitis B virus X protein involved in hepatitis B virus-related hepatocarcinogenesis in HepG2 cell lines

Hepatitis B virus (HBV) infection-related hepatocellular carcinoma (HCC) represents a major health problem worldwide. HBV X (HBx) protein is the most common open reading frame that may undergo mutations, resulting in the development of HCC. This study aimed to determine specific HBx mutations that d...

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Detalhes bibliográficos
Publicado no:Cancer Lett
Main Authors: Shi, Ying, Wang, Junwei, Wang, Yuhe, Wang, Anna, Guo, Hongliang, Wei, Feili, Mehta, Sanjay R., Espitia, Stephen, Smith, Davey M., Liu, Longgen, Zhang, Yulin, Chen, Dexi
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4934374/
https://ncbi.nlm.nih.gov/pubmed/26706415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2015.12.008
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