T-cell activation is enhanced by targeting IL-10 cytokine production in toll-like receptor-stimulated macrophages

Toll-like receptor (TLR) agonists represent potentially useful cancer vaccine adjuvants in their ability to stimulate antigen-presenting cells (APCs) and subsequently amplify the cytotoxic T-cell response. The purpose of this study was to characterize APC responses to TLR activation and to determine...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Immunotargets Ther
Hauptverfasser: Walk, Ryan M, Elliott, Steven T, Blanco, Felix C, Snyder, Jason A, Jacobi, Ashley M, Rose, Scott D, Behlke, Mark A, Salem, Aliasger K, Vukmanovic, Stanislav, Sandler, Anthony D
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2012
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4934151/
https://ncbi.nlm.nih.gov/pubmed/27471682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/ITT.S32615
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge