T-cell activation is enhanced by targeting IL-10 cytokine production in toll-like receptor-stimulated macrophages

Toll-like receptor (TLR) agonists represent potentially useful cancer vaccine adjuvants in their ability to stimulate antigen-presenting cells (APCs) and subsequently amplify the cytotoxic T-cell response. The purpose of this study was to characterize APC responses to TLR activation and to determine...

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Publicado en:Immunotargets Ther
Autores principales: Walk, Ryan M, Elliott, Steven T, Blanco, Felix C, Snyder, Jason A, Jacobi, Ashley M, Rose, Scott D, Behlke, Mark A, Salem, Aliasger K, Vukmanovic, Stanislav, Sandler, Anthony D
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove Medical Press 2012
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4934151/
https://ncbi.nlm.nih.gov/pubmed/27471682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/ITT.S32615
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