Pro-fibrotic pathway activation in trabecular meshwork and lamina cribrosa is the main driving force of glaucoma

While primary open-angle glaucoma (POAG) is a leading cause of blindness worldwide, it still does not have a clear mechanism that can explain all clinical cases of the disease. Elevated IOP is associated with increased accumulation of extracellular matrix (ECM) proteins in the trabecular meshwork (T...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Zhavoronkov, Alex, Izumchenko, Evgeny, Kanherkar, Riya R., Teka, Mahder, Cantor, Charles, Manaye, Kebreten, Sidransky, David, West, Michael D., Makarev, Eugene, Csoka, Antonei Benjamin
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
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Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4934076/
https://ncbi.nlm.nih.gov/pubmed/27229292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1170261
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