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Ligation-free ribosome profiling of cell type-specific translation in the brain

Ribosome profiling has emerged as a powerful tool for genome-wide measurements of translation, but library construction requires multiple ligation steps and remains cumbersome relative to more conventional deep-sequencing experiments. We report a new, ligation-free approach to ribosome profiling tha...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Hornstein, Nicholas, Torres, Daniela, Das Sharma, Sohani, Tang, Guomei, Canoll, Peter, Sims, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4934013/
https://ncbi.nlm.nih.gov/pubmed/27380875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-1005-1
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