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Antibody-Dependent Enhancement of Dengue Virus Infection in Primary Human Macrophages; Balancing Higher Fusion against Antiviral Responses

The dogma is that the human immune system protects us against pathogens. Yet, several viruses, like dengue virus, antagonize the hosts’ antibodies to enhance their viral load and disease severity; a phenomenon called antibody-dependent enhancement of infection. This study offers novel insights in th...

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Publicado no:Sci Rep
Main Authors: Flipse, Jacky, Diosa-Toro, Mayra A., Hoornweg, Tabitha E., van de Pol, Denise P. I., Urcuqui-Inchima, Silvio, Smit, Jolanda M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933910/
https://ncbi.nlm.nih.gov/pubmed/27380892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29201
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