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Antibody-Dependent Enhancement of Dengue Virus Infection in Primary Human Macrophages; Balancing Higher Fusion against Antiviral Responses

The dogma is that the human immune system protects us against pathogens. Yet, several viruses, like dengue virus, antagonize the hosts’ antibodies to enhance their viral load and disease severity; a phenomenon called antibody-dependent enhancement of infection. This study offers novel insights in th...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Flipse, Jacky, Diosa-Toro, Mayra A., Hoornweg, Tabitha E., van de Pol, Denise P. I., Urcuqui-Inchima, Silvio, Smit, Jolanda M.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933910/
https://ncbi.nlm.nih.gov/pubmed/27380892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29201
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