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Efficient nucleic acid delivery to murine regulatory T cells by gold nanoparticle conjugates

Immune responses have to be tightly controlled to guarantee maintenance of immunological tolerance and efficient clearance of pathogens and tumorigenic cells without induction of unspecific side effects. CD4(+) CD25(+) regulatory T cells (Tregs) play an important role in these processes due to their...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Gamrad, Lisa, Rehbock, Christoph, Westendorf, Astrid M., Buer, Jan, Barcikowski, Stephan, Hansen, Wiebke
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933883/
https://ncbi.nlm.nih.gov/pubmed/27381215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28709
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