Group II mGlu receptor antagonist LY341495 enhances the antidepressant-like effects of ketamine in the forced swim test in rats

RATIONALE: Numerous preclinical and clinical studies have reported the rapid and sustained antidepressant effects of the NMDA receptor antagonist ketamine. Because ketamine induces several undesirable and dangerous effects, a variety of strategies have been suggested to avoid such effects. OBJECTIVE...

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Bibliographic Details
Published in:Psychopharmacology (Berl)
Main Authors: Podkowa, Karolina, Pochwat, Bartłomiej, Brański, Piotr, Pilc, Andrzej, Pałucha-Poniewiera, Agnieszka
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2016
Subjects:
Original Investigation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933730/
https://ncbi.nlm.nih.gov/pubmed/27286960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-016-4325-7
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