Reduced Nrf2 expression mediates the decline in neural stem cell function during a critical middle‐age period

Although it is known that the regenerative function of neural stem/progenitor cells (NSPCs) declines with age, causal mechanisms underlying this phenomenon are not understood. Here, we systematically analyze subventricular zone (SVZ) NSPCs, in various groups of rats across the aging spectrum, using...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Corenblum, Mandi J., Ray, Sneha, Remley, Quentin W., Long, Min, Harder, Bryan, Zhang, Donna D., Barnes, Carol A., Madhavan, Lalitha
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933666/
https://ncbi.nlm.nih.gov/pubmed/27095375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12482
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