Ultrastructure of the liver microcirculation influences hepatic and systemic insulin activity and provides a mechanism for age‐related insulin resistance

While age‐related insulin resistance and hyperinsulinemia are usually considered to be secondary to changes in muscle, the liver also plays a key role in whole‐body insulin handling and its role in age‐related changes in insulin homeostasis is largely unknown. Here, we show that patent pores called...

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Enregistré dans:
Détails bibliographiques
Publié dans:Aging Cell
Auteurs principaux: Mohamad, Mashani, Mitchell, Sarah Jayne, Wu, Lindsay Edward, White, Melanie Yvonne, Cordwell, Stuart James, Mach, John, Solon‐Biet, Samantha Marie, Boyer, Dawn, Nines, Dawn, Das, Abhirup, Catherine Li, Shi‐Yun, Warren, Alessandra, Hilmer, Sarah Nicole, Fraser, Robin, Sinclair, David Andrew, Simpson, Stephen James, de Cabo, Rafael, Le Couteur, David George, Cogger, Victoria Carroll
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2016
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933657/
https://ncbi.nlm.nih.gov/pubmed/27095270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12481
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