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Viricidal effect of stimulated human mononuclear phagocytes on human immunodeficiency virus type 1.

Human monocytes stimulated with phorbol 12-myristate 13-acetate or opsonized zymosan in vitro were viricidal to human immunodeficiency virus type 1 (HIV-1) as measured by the inability of the virus to replicate in CEM cells. Monocytes, when stimulated, release myeloperoxidase (MPO) and produce H2O2;...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Chase, M J, Klebanoff, S J
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1992
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49336/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1319066/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.12.5582
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