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DNA Interactions Probed by Hydrogen-Deuterium Exchange (HDX) Fourier Transform Ion Cyclotron Resonance Mass Spectrometry Confirm External Binding Sites on the Minichromosomal Maintenance (MCM) Helicase

The archaeal minichromosomal maintenance (MCM) helicase from Sulfolobus solfataricus (SsoMCM) is a model for understanding structural and mechanistic aspects of DNA unwinding. Although interactions of the encircled DNA strand within the central channel provide an accepted mode for translocation, int...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Graham, Brian W., Tao, Yeqing, Dodge, Katie L., Thaxton, Carly T., Olaso, Danae, Young, Nicolas L., Marshall, Alan G., Trakselis, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933441/
https://ncbi.nlm.nih.gov/pubmed/27044751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.719591
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