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CRISPR-directed mitotic recombination enables genetic mapping without crosses
Linkage and association studies have mapped thousands of genomic regions that contribute to phenotypic variation, but narrowing these regions to the underlying causal genes and variants has proven much more challenging. Resolution of genetic mapping is limited by the recombination rate. We developed...
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| Pubblicato in: | Science |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4933295/ https://ncbi.nlm.nih.gov/pubmed/27230379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaf5124 |
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