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A Conserved C-terminal Element in the Yeast Doa10 and Human MARCH6 Ubiquitin Ligases Required for Selective Substrate Degradation

Specific proteins are modified by ubiquitin at the endoplasmic reticulum (ER) and are degraded by the proteasome, a process referred to as ER-associated protein degradation. In Saccharomyces cerevisiae, two principal ER-associated protein degradation ubiquitin ligases (E3s) reside in the ER membrane...

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Vydáno v:J Biol Chem
Hlavní autoři: Zattas, Dimitrios, Berk, Jason M., Kreft, Stefan G., Hochstrasser, Mark
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933261/
https://ncbi.nlm.nih.gov/pubmed/27068744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.726877
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