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Simultaneous all-optical manipulation and recording of neural circuit activity with cellular resolution in vivo
We describe an all-optical strategy for simultaneously manipulating and recording the activity of multiple neurons with cellular resolution in vivo. Concurrent two-photon optogenetic activation and calcium imaging is enabled by coexpression of a red-shifted opsin and a genetically encoded calcium in...
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| Published in: | Nat Methods |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4933203/ https://ncbi.nlm.nih.gov/pubmed/25532138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3217 |
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