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Characterization of the Regulation of CD46 RNA Alternative Splicing

Here we present a detailed analysis of the alternative splicing regulation of human CD46, which generates different isoforms with distinct functions. CD46 is a ubiquitous membrane protein that protects host cells from complement and plays other roles in immunity, autophagy, and cell adhesion. CD46 d...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Tang, Sze Jing, Luo, Shufang, Ho, Jia Xin Jessie, Ly, Phuong Thao, Goh, Eling, Roca, Xavier
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2016
Teme:
RNA
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933185/
https://ncbi.nlm.nih.gov/pubmed/27226545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.710350
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