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Tranilast Blocks the Interaction between the Protein S100A11 and Receptor for Advanced Glycation End Products (RAGE) V Domain and Inhibits Cell Proliferation

The human S100 calcium-binding protein A11 (S100A11) is a member of the S100 protein family. Once S100A11 proteins bind to calcium ions at EF-hand motifs, S100A11 changes its conformation, promoting interaction with target proteins. The receptor for advanced glycation end products (RAGE) consists of...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Huang, Yen-Kai, Chou, Ruey-Hwang, Yu, Chin
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933184/
https://ncbi.nlm.nih.gov/pubmed/27226584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.722215
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