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Human RNA Polymerase II Promoter Recruitment in Vitro Is Regulated by O-Linked N-Acetylglucosaminyltransferase (OGT)
Although the O-linked N-acetylglucosamine (O-GlcNAc) modification of the RNA polymerase II C-terminal domain was described 20 years ago, the function of this RNA polymerase II (pol II) species is not known. We show here that an O-GlcNAcylated pol II species (pol IIγ) exists on promoters in vitro. In...
Shranjeno v:
izdano v: | J Biol Chem |
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Main Authors: | , , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
American Society for Biochemistry and Molecular Biology
2016
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4933165/ https://ncbi.nlm.nih.gov/pubmed/27129214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.684365 |
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