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Human RNA Polymerase II Promoter Recruitment in Vitro Is Regulated by O-Linked N-Acetylglucosaminyltransferase (OGT)

Although the O-linked N-acetylglucosamine (O-GlcNAc) modification of the RNA polymerase II C-terminal domain was described 20 years ago, the function of this RNA polymerase II (pol II) species is not known. We show here that an O-GlcNAcylated pol II species (pol IIγ) exists on promoters in vitro. In...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Lewis, Brian A., Burlingame, Alma L., Myers, Samuel A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933165/
https://ncbi.nlm.nih.gov/pubmed/27129214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.684365
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