Highly specific SNP detection using 2D graphene electronics and DNA strand displacement

Single-nucleotide polymorphisms (SNPs) in a gene sequence are markers for a variety of human diseases. Detection of SNPs with high specificity and sensitivity is essential for effective practical implementation of personalized medicine. Current DNA sequencing, including SNP detection, primarily uses...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Hwang, Michael T., Landon, Preston B., Lee, Joon, Choi, Duyoung, Mo, Alexander H., Glinsky, Gennadi, Lal, Ratnesh
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2016
Fag:
Physical Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4932965/
https://ncbi.nlm.nih.gov/pubmed/27298347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1603753113
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