Phase I/II study of first-line irinotecan combined with 5-fluorouracil and folinic acid Mayo Clinic schedule in patients with advanced colorectal cancer

BACKGROUND: This multicentre phase I/II study was designed to determine the maximum tolerated dose of irinotecan when combined with 5-fluorouracil and folinic acid according to the Mayo Clinic schedule and to evaluate the activity of this combination as first-line therapy in patients with advanced c...

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Detalhes bibliográficos
Main Authors: Kuehr, Thomas, Ruff, Paul, Rapoport, Bernardo L, Falk, Stephen, Daniel, Francis, Jacobs, Conrad, Davidson, Neville, Thaler, Josef, Boussard, Blandine, Carmichael, James
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2004
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC493270/
https://ncbi.nlm.nih.gov/pubmed/15257756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-4-36
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