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AAV Natural Infection Induces Broad Cross-Neutralizing Antibody Responses to Multiple AAV Serotypes in Chimpanzees

Cross-sectional studies of primates have revealed that natural neutralizing antibody (NAb) responses to adeno-associated viruses (AAV) span multiple serotypes. This differs from the phenotype of the NAb response to an AAV vector delivered to seronegative nonhuman primates that is typically restricte...

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Detalhes bibliográficos
Publicado no:Hum Gene Ther Clin Dev
Main Authors: Calcedo, Roberto, Wilson, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4932656/
https://ncbi.nlm.nih.gov/pubmed/27314914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/humc.2016.048
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