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Chemical Variations on the p53 Reactivation Theme
Among the tumor suppressor genes, p53 is one of the most studied. It is widely regarded as the “guardian of the genome”, playing a major role in carcinogenesis. In fact, direct inactivation of the TP53 gene occurs in more than 50% of malignancies, and in tumors that retain wild-type p53 status, its...
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| Publicado no: | Pharmaceuticals (Basel) |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4932543/ https://ncbi.nlm.nih.gov/pubmed/27187415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph9020025 |
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