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COL4A6 is dispensable for autosomal recessive Alport syndrome

Alport syndrome is caused by mutations in the genes encoding α3, α4, or α5 (IV) chains. Unlike X-linked Alport mice, α5 and α6 (IV) chains are detected in the glomerular basement membrane of autosomal recessive Alport mice, however, the significance of this finding remains to be investigated. We the...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Murata, Tomohiro, Katayama, Kan, Oohashi, Toshitaka, Jahnukainen, Timo, Yonezawa, Tomoko, Sado, Yoshikazu, Ishikawa, Eiji, Nomura, Shinsuke, Tryggvason, Karl, Ito, Masaaki
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4932521/
https://ncbi.nlm.nih.gov/pubmed/27377778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29450
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