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COL4A6 is dispensable for autosomal recessive Alport syndrome

Alport syndrome is caused by mutations in the genes encoding α3, α4, or α5 (IV) chains. Unlike X-linked Alport mice, α5 and α6 (IV) chains are detected in the glomerular basement membrane of autosomal recessive Alport mice, however, the significance of this finding remains to be investigated. We the...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Murata, Tomohiro, Katayama, Kan, Oohashi, Toshitaka, Jahnukainen, Timo, Yonezawa, Tomoko, Sado, Yoshikazu, Ishikawa, Eiji, Nomura, Shinsuke, Tryggvason, Karl, Ito, Masaaki
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4932521/
https://ncbi.nlm.nih.gov/pubmed/27377778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29450
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