Childhood asthma exacerbations and the Arg-16 beta2 receptor polymorphism: a meta-analysis stratified by treatment

BACKGROUND: The Gly-to-Arg substitution at the 16 position (rs1042713) in the beta 2 adrenoceptor (ADRB2) gene is associated with enhanced down-regulation and uncoupling of beta-2 receptors. OBJECTIVES: To undertake a meta-analysis to test the hypothesis that there is an interaction between the A al...

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Publicado en:J Allergy Clin Immunol
Main Authors: Turner, Steve, Francis, Ben, Vijverberg, Susanne, Pino-Yanes, Maria, Maitland-van der Zee, Anke H, Basu, Kaninika, Bignell, Lauren, Mukhopadhyay, Somnath, Tavendale, Roger, Palmer, Colin, Hawcutt, Daniel, Pirmohamed, Munir, Burchard, Esteban G, Lipworth, Brian
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4931969/
https://ncbi.nlm.nih.gov/pubmed/26774659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2015.10.045
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