The Nucleus Accumbens: Mechanisms of Addiction across Drug Classes Reflect the Importance of Glutamate Homeostasis

The nucleus accumbens is a major input structure of the basal ganglia and integrates information from cortical and limbic structures to mediate goal-directed behaviors. Chronic exposure to several classes of drugs of abuse disrupts plasticity in this region, allowing drug-associated cues to engender...

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Dettagli Bibliografici
Pubblicato in:Pharmacol Rev
Autori principali: Scofield, M. D., Heinsbroek, J. A., Gipson, C. D., Kupchik, Y. M., Spencer, S., Smith, A. C. W., Roberts-Wolfe, D., Kalivas, P. W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Pharmacology and Experimental Therapeutics 2016
Soggetti:
Review Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4931870/
https://ncbi.nlm.nih.gov/pubmed/27363441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/pr.116.012484
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