The effects of graded levels of calorie restriction: VII. Topological rearrangement of hypothalamic aging networks

Connectivity in a gene-gene network declines with age, typically within gene clusters. We explored the effect of short-term (3 months) graded calorie restriction (CR) (up to 40 %) on network structure of aging-associated genes in the murine hypothalamus by using conditional mutual information. The n...

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Vydáno v:Aging (Albany NY)
Hlavní autoři: Derous, Davina, Mitchell, Sharon E., Green, Cara L., Wang, Yingchun, Han, Jing Dong J., Chen, Luonan, Promislow, Daniel E.L., Lusseau, David, Speakman, John R., Douglas, Alex
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4931844/
https://ncbi.nlm.nih.gov/pubmed/27115072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.100944
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